ea0081oc9.1 | Oral Communications 9: Environmental Endocrinology | ECE2022
Jensen Richard Christian
, Glintborg Dorte
, Timmermann Clara Amalie Gade
, Nielsen Flemming
, Boye Henriette
, Bilenberg Niels
, Madsen Jeppe Buur
, Grandjean Philippe
, Jensen Tina Kold
, Andersen Marianne
Background: Perfluoroalkyl substances (PFAS) are endocrine disrupting chemicals, with elimination half-lives ranging from four to eight years. Experimental studies found PFAS able to interfere with thyroid hormone-binding proteins. During the first 20 weeks of gestation (GW), the fetus is reliant on placental transfer of maternal thyroid hormones, mainly free thyroxine (FT4). However, previous studies investigating associations between exposure to PFAS and thyroid hormone stat...